Synonymous Codon Usage Bias in Porcine Epidemic Diarrhea Virus
نویسندگان
چکیده
ABST RACT In this study, we analyzed the synonymous codon usage bias in porcine epidemic diarrhea virus genome. The effective number of codons (ENC) and the relative synonymous codon usage (RSCU) values are used to estimate codon usage variation. The plot of ENC values against GC3s and correlation analysis revealed that mutational pressure rather than translational selection is the main factor determining the codon usage bias in porcine epidemic diarrhea virus. In addition, other factors, such as aromaticity, hydrophobicity of genes also influenced the codon usage variation among virus genomes in a minor way. Our work might contribute to the understanding of molecular evolution of codon usage variation in porcine epidemic diarrhea virus genome.
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